Overactive Bladder (OAB)

The bladder is a muscle, and spasms of the bladder muscle can cause urinary urgency and/ or frequency among people with Parkinson’s. Lifestyle changes can be of some benefit in reducing OAB: weight loss, reducing consumption of alcohol and caffeine, and reducing fluid intake at night. Pelvic floor strengthening with Kegel exercises can be helpful. Medications can also reduce the bladder spasms of OAB. Possible side effects include headache, constipation, dry mouth, blurry vision, and urinary retention. Most OAB medications work via anticholinergic effects, and they can have the side effects of anticholinergic medications (see Anticholinergic Medication)

Generic Name
Trade Name
Notes
Link
Patient Assistance
Brochure
Trospium Sanctura Product Website Teva Patient Assistance
Darifenacin Enablex Prescribing Information Allergan Patient Assistance
Tolterodine Detrol Product Website Pfizer Savings Program More Information
Fesoterodine Toviaz Product Website Pfizer Patient Assistance More Information
Solifenacin Vesicare Not recommended for people at high risk of QT prolongation. Product Website Astellas Pharma Patient Assistance More Information
Oxybutynin Ditropan Crosses into the brain more than other OAB medications, may be more likely to worsen confusion. Prescribing Information Teva Patient Assistance
Mirabegron Myrbetriq Unlike the other OAB medications (which are anticholinergic), this medication is a beta-3 agonist. Less likely than other OAB medications to cause cognitive side effects. Should not be used by people with uncontrolled hypertension. Product Website Astellas Savings and Support

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