Hallucinations/Delusions (Psychosis)

Hallucinations refers to seeing or hearing things that aren't there. Delusions refers to believing things that are not true. The presence of hallucinations or delusions is technically known as psychosis. These symptoms may range from mild to severe. Possible side effects include drowsiness, low blood pressure, and constipation.

Generic Name
Trade Name
Patient Assistance
Rivastigmine, donepezil, galantamine Exelon, Aricept, Razadyne See chart for information about dementia.
Pimavanserin Nuplazid Only medication specifically approved by the FDA for Parkinson's psychosis. Less sedating than quetiapine. May cause edema. Product Website Acadia Patient Assistance More Information
Quetiapine Seroquel, Seroquel SR Off-label for Parkinson's psychosis. Can be sedating, so often dosed at bedtime. May cause sleepiness, dizziness, dry mouth, orthostatic hypotension, and weight gain. Prescribing Information AstraZeneca Savings Program
Clozapine Clozaril Off-label for Parkinson's psychosis. More evidence of benefit than quetiapine but used less frequently due to requirement for weekly blood tests to check for low white blood cell counts. May have some benefit for tremor. May cause sleepiness, dizziness, drooling, tachycardia, and rarely seizures. Product Website HLS Therapeutics Patient Assistance

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