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Other Antidepressants

About Other Antidepressants

These medications can also have benefit for depression, anxiety, and OCD. Like SSRIs, SNRIs, and TCAs, it often takes four to six weeks after reaching a therapeutic dose for these drugs to take effect. Some of these medications should be used with caution in conjunction with serotonergic medications due to a potential for serotonin syndrome.

Generic NameTrade NameNotesLinkPatient AssistanceBrochure
BupropionWellbutrin®, Wellbutrin® XL

Less likely than other antidepressants to cause weight gain or sexual side effects. More likely than other side antidepressants to have tremor as a side effect.

Product WebsiteBausch Savings ProgramMore Information
MirtazapineRemeron®

May cause sedation (also used to help with insomnia) or increased appetite (also used to help with weight gain). Also available as a dissolvable pill, which can be an advantage for people with swallowing problems.

Prescribing InformationMerck Patient Assistance
TrazodoneDesyrel®, Oleptro™, Trialodine® May cause sedation (also used to help with insomnia). Product WebsiteTeva Patient Assistance
VilazodoneViibryd® Product WebsiteViibryd Savings Program
VortioxetineTrintellix®